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Allele : Mark3<tm1Hpw> MAP/microtubule affinity regulating kinase 3; targeted mutation 1, Helen Piwnica-Worms

Primary Identifier  MGI:3836595 Allele Type  Targeted
Attribute String  Null/knockout Gene  Mark3
Transmission  Germline Strain of Origin  129X1/SvJ
Is Recombinase  false Is Wild Type  false
molecularNote  A 1.9 kb fragment of the gene was disrupted by the insertion of a neomycin resistance cassette. Exon 2 (hosting the ATP binding site) and the 5' slice site of intron 2/3 were shifted out of frame. Multi-tissue Western blotting confirmed ablation of this gene in all tissues of homozygous null-mice.
  • mutations:
  • Insertion
  • synonyms:
  • Par-1a<->,
  • Par-1a<->,
  • cTak KO,
  • cTak KO
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1 Feature

Trail: Allele

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

1 Carried By

Trail: Allele

0 Driven By

3 Publication categories

Trail: Allele