Primary Identifier | MGI:2180672 | Allele Type | Targeted |
Attribute String | Null/knockout | Gene | Rel |
Transmission | Germline | Strain of Origin | 129S4/SvJae |
Is Recombinase | false | Is Wild Type | false |
molecularNote | Exon 5 (which encodes amino acids 102-130) was replaced with a neomycin resistance gene via homologous recombination. Western blot assay of spleen lysates from homozygous mutant animals verified the absence of gene expression. |