Primary Identifier | MGI:4431078 | Allele Type | Targeted |
Attribute String | Not Specified | Gene | Ppp1r3b |
Transmission | Germline | Strain of Origin | C57BL/6N |
Is Recombinase | false | Is Wild Type | false |
molecularNote | An A to T substitution within exon 2 results in the amino acid substitution of phenylalanine for tyrosine at position 284 (Y284F). This allele is critical for binding to phosphorylase a. An frt flanked neo cassette used for selection purposes was removed by flp mediated recombination leaving a single frt site upstream of exon 2. |