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Transgene : Tg(DMD-APP*)18Neve transgene insertion 18, Rachel L Neve

Primary Identifier  MGI:3720648 Organism  mouse, laboratory
Chromosome  UN Mgi Type  transgene
description  PHENOTYPE: Transgenic mice express the FLAGC100 fragment of APP at hign levels in the brain. Amyloid peptide (AB1-42 accumulation is detected in neurons, primarily in the hippocampus at ~4 months of age. Animals develop marked neurodegeneration by ~1 year of age. [provided by MGI curators]
  • synonyms:
  • FLAGC100,
  • transgene insertion 18, Rachel L Neve,
  • Tg(DMD-APP*)18Neve

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Genome

Sequence Feature Displayer

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Canonical gene --> CDSs in specific strains.

Canonical gene --> Exons in specific strains

Canonical gene --> Strain-specific IDs, biotypes, and locations

Canonical gene --> Transcripts in specific strains.

Features --> Overlapping features

Proteins

Gene --> Proteins

Function

Mouse features --> Functions (GO terms)

Homology

Genes --> Homologs

Interactions

Gene --> Protein-Protein Interactions

Expression

Gene --> Expression annotations

Phenotype

Genes/Features --> Phenotypes (MP terms)

Disease

Mouse features --> Human diseases

Literature

Mouse features --> Publications

 

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