| Primary Identifier | MGI:2384433 | Allele Type | Targeted |
| Attribute String | Null/knockout | Gene | Egr1 |
| Transmission | Germline | Strain of Origin | 129 |
| Is Recombinase | false | Is Wild Type | false |
| description | ES cell line = AB1 (129S7/SvEvBrd-Hprt+) or D3 (129S2/SvPas). |
| molecularNote | The gene was disrupted by insertion of a PGK-neo cassette into a coding exon upstream of the DNA-binding domain via homologous recombination. The targeted mutation introduces several stop codons resulting protein truncation upstream of the DNA-binding domain. Gene expression and protein product were not observed in homozygous mutant ES cells. |
