Primary Identifier | MGI:2157371 | Allele Type | Targeted |
Attribute String | Null/knockout, Reporter | Gene | Il1a |
Transmission | Germline | Strain of Origin | (129X1/SvJ x 129S1/Sv)F1-Kitl<+> |
Is Recombinase | false | Is Wild Type | false |
molecularNote | A lacZ-PGK-hygromycin expression cassette replaced 1.5kb of sequence, including the region in exon 5 that encodes the amino terminal region of the mature protein. Northern blot analysis of activated peritoneal macrophages did not detect transcript in homozygous mutant mice. |