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Allele : Il1a<tm1Yiw> interleukin 1 alpha; targeted mutation 1, Yoichiro Iwakura

Primary Identifier  MGI:2157371 Allele Type  Targeted
Attribute String  Null/knockout, Reporter Gene  Il1a
Transmission  Germline Strain of Origin  (129X1/SvJ x 129S1/Sv)F1-Kitl<+>
Is Recombinase  false Is Wild Type  false
molecularNote  A lacZ-PGK-hygromycin expression cassette replaced 1.5kb of sequence, including the region in exon 5 that encodes the amino terminal region of the mature protein. Northern blot analysis of activated peritoneal macrophages did not detect transcript in homozygous mutant mice.
  • mutations:
  • Intragenic deletion,
  • Insertion
  • synonyms:
  • IL-1alpha KO,
  • IL-1alpha-,
  • IL-1alpha-,
  • IL-1alpha KO
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1 Feature

Trail: Allele

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

1 Carried By

Trail: Allele

0 Driven By

171 Publication categories

Trail: Allele