| Primary Identifier | MGI:4442928 | Allele Type | Targeted |
| Gene | Arl6 | Transmission | Germline |
| Strain of Origin | (129X1/SvJ x 129S1/Sv)F1-Kitl<+> | Is Recombinase | false |
| Is Wild Type | false |
| molecularNote | The splice acceptor and splice donor sites of exon 8 were mutated (AG->AC and GT->CT, respectively) and a neo cassette was inserted downstream of the modified exon 8. The nucleotide substitutions are predicted to result in the exclusion of exon 8 of the long transcript. RT-PCR confirmed the expression of the modified allele. |
