| Primary Identifier | MGI:7521957 | Allele Type | Endonuclease-mediated |
| Gene | Tbr1 | Strain of Origin | C57BL/6NJ |
| Is Recombinase | false | Is Wild Type | false |
| molecularNote | Glutamic acid codon 348 through proline codon 353 in exon 4 were deleted (c.1042_1059del, p.E348_P353delEDTSQP) using an sgRNA and an ssODN template with CRISPR/cas9 technology. The mutation is in the T-box and includes five human TBR1 variants identified as pathogenic or likely pathogenic. |
