| Primary Identifier | MGI:3696870 | Allele Type | Transgenic |
| Attribute String | Inserted expressed sequence | Gene | Tg(Smgb-TAg)8Mir |
| Strain of Origin | (BALB/cJ x C57BL/6J)F1 | Is Recombinase | false |
| Is Wild Type | false |
| description | Five lines were created: 8, 22, 41, 43, and 49. Mice from lines 41 and 49 succumbed to pancreatic tumors between 3 and 4 months of age. Mice from lines 22 and 43 did not develop tumors after one year of observation. In line 8, 3 out 7 males developed tumors. Line 8 was studied further. |
| molecularNote | Promoter elements including -10.5 kb to +30 of the rat Smgb salivary protein gene were used to drive the expression of SV40 T antigen. The transgene is expressed in the intercalated duct cells of the submandibular gland. |
