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Allele : Cdc25a<m1Rfp> cell division cycle 25A; mutation 1, Robert F Paulson

Primary Identifier  MGI:2445422 Allele Type  Spontaneous
Gene  Cdc25a Strain of Origin  BALB/cJ
Is Recombinase  false Is Wild Type  false
molecularNote  A transversion mutation (C to A) resulted in a histidine to glutamine substitution at codon 128. The mutation is in a region of 24 conserved residues in the amino terminal non-catalytic domain and was demonstrated by biochemical assays to confer increased phosphatase activity. Identification of this allele was facilitated by linkage to Mst1rFv2.
  • mutations:
  • Single point mutation
  • synonyms:
  • Cdc25A<His128Gln>,
  • Cdc25A<His128Gln>
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1 Feature

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

0 Carried By

0 Driven By

3 Publication categories