Primary Identifier | MGI:5312109 | Allele Type | Transgenic |
Attribute String | Inserted expressed sequence | Gene | Tg(HLA-DRA*0101,HLA-DRB1*0101)1Dma |
Strain of Origin | FVB/N | Is Recombinase | false |
Is Wild Type | false |
molecularNote | This transgene was generated by coinjection of cosmid inserts of ~24 and ~22 kb, respectively, containing the complete human major histocompatibility (MHC) class II gene alleles HLA-DRA*0101 and HLA-DRB1*0101, each with several kilobases of flanking sequence. The resulting transgenic mice express human serotype HLA-DR1. |