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Allele : Tmc1<stitch> transmembrane channel-like gene family 1; stitch

Primary Identifier  MGI:5314996 Allele Type  Chemically induced (ENU)
Gene  Tmc1 Inheritance Mode  Recessive
Strain of Origin  C57BL/6 Is Recombinase  false
Is Wild Type  false
molecularNote  ENU induced a G to T mutation at position 1661 resulting in a tryptophan to leucine substitution at amino acid 554 in exon 15 and is predicted to alter protein folding. Protein expression is reduced in the type III fibrocytes basal to mid cochlear region but increased in the apical region in homozygous mice.
  • mutations:
  • Single point mutation
  • synonyms:
  • Tmc1<W554L>,
  • Tmc1<W554L>
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1 Feature

Trail: Allele

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

0 Carried By

0 Driven By

3 Publication categories

Trail: Allele