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Allele : Npm1<tm2Ppp> nucleophosmin 1; targeted mutation 2, Pier Paolo Pandolfi

Primary Identifier  MGI:3604808 Allele Type  Targeted
Attribute String  Hypomorph Gene  Npm1
Transmission  Germline Strain of Origin  Not Specified
Is Recombinase  false Is Wild Type  false
molecularNote  An Frt-flanked neomycin resistance cassette was inserted into intron 6. Mutant mice expressed protein at levels reduced to about 10-30% of wild-type levels. LoxP sites were inserted to flank exons 1 to 6, encompassing the inserted neo.
  • mutations:
  • Insertion
  • synonyms:
  • Npm<hyp>,
  • Npm<hyp>
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1 Feature

Trail: Allele

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

0 Carried By

0 Driven By

5 Publication categories

Trail: Allele