Primary Identifier | MGI:5488499 | Allele Type | Targeted |
Attribute String | Null/knockout | Gene | Cxcl12 |
Transmission | Germline | Strain of Origin | B6.Cg-Thy1<a> |
Is Recombinase | false | Is Wild Type | false |
molecularNote | A loxP site was inserted 5' of exon 2 and an Frt-Neo-Frt-loxP cassette was placed 3' of the same exon. The selection cassette was subsequently removed by crossing with mice expressing flp recombinase. Germline cre expression excised exon 2 and created a frame shift mutation. |