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Allele : Aplp2<tm1Dbo> amyloid beta precursor-like protein 2; targeted mutation 1, David R Borchelt

Primary Identifier  MGI:2137246 Allele Type  Targeted
Attribute String  Null/knockout Gene  Aplp2
Transmission  Germline Strain of Origin  129S7/SvEvBrd-Hprt1<b-m2>
Is Recombinase  false Is Wild Type  false
molecularNote  Replacement of the promoter region and first exon with a neomycin cassette. Western blot analysis on samples derived from nervous tissue and other peripheral tissues of homozygous mutant mice failed to detect any protein.
  • mutations:
  • Insertion,
  • Intragenic deletion
  • synonyms:
  • APLP2<->,
  • APLP2<->
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1 Feature

Trail: Allele

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

2 Carried By

Trail: Allele

0 Driven By

51 Publication categories

Trail: Allele