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Allele : Gt(ROSA)26Sor<tm11(ACTB-EGFP*)Luo> gene trap ROSA 26, Philippe Soriano; targeted mutation 11, Liqun Luo
Primary Identifier  MGI:5314257 Allele Type  Targeted
Attribute String  Reporter Gene  Gt(ROSA)26Sor
Transmission  Germline Strain of Origin  (129X1/SvJ x 129S1/Sv)F1-Kitl<+>
Is Recombinase  false Is Wild Type  false
molecularNote  Cre-mediated recombination between Gt(ROSA)26Sortm6(ACTB-EGFP*,-tdTomato)Luo and Gt(ROSA)26Sortm7(ACTB-EGFP*)Luo produces this allele. The allele has the CMV enhancer/chicken beta-actin core promoter (pCA) upstream of the recombined "MADM GG" cassette inserted into the Gt(ROSA)26Sor locus. The "MADM GG" cassette has the N-terminal portion of a mutant enhanced green fluorescent protein (mut4EGFP first exon; nucleotide 1-274), a beta-globin intronic sequence (containing a frt-flanked region of two lox site variants [lox2272 and lox5171] followed by a single loxP site), the C-terminal portion of a mutant enhanced green fluorescent protein (mut4EGFP second exon; nucleotides 275-735 including stop codon), and an SV40 T-antigen poly(A) signal.
  • mutations:
  • Insertion
  • synonyms:
  • R26<GG>,
  • R26<GG>
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1 Feature

Trail: Allele

Genome

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0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

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