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Allele : Kcnj3<tm1Kwn> potassium inwardly-rectifying channel, subfamily J, member 3; targeted mutation 1, Kevin D Wickman

Primary Identifier  MGI:2447632 Allele Type  Targeted
Attribute String  Null/knockout Gene  Kcnj3
Transmission  Germline Strain of Origin  129X1/SvJ
Is Recombinase  false Is Wild Type  false
molecularNote  Exon 3 was deleted by homologous and cre mediated recombination in ES cells. The deleted sequence encoded the pore and transmembrane domains, the entire amino terminus, and the initiator methionine. Normal protein was undetected by Western blot analysis of atrial tissue obtained from homozygous mutant mice.
  • mutations:
  • Insertion,
  • Intragenic deletion
  • synonyms:
  • Kir3.1 knock-out,
  • Kir3.1 knock-out,
  • GIRK1 KO,
  • GIRK1 KO
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1 Feature

Trail: Allele

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

1 Carried By

Trail: Allele

0 Driven By

22 Publication categories

Trail: Allele