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Allele : Ager<tm1.1Arnd> advanced glycosylation end product-specific receptor; targeted mutation 1.1, Bernd Arnold
Primary Identifier  MGI:2451038 Allele Type  Targeted
Attribute String  Null/knockout, Reporter Gene  Ager
Transmission  Germline Strain of Origin  129P2/OlaHsd
Is Recombinase  false Is Wild Type  false
molecularNote  An EGFP reporter gene followed by a single loxP site was inserted into intron 1 in reverse transcriptional orientation to the gene. A neomycin selection gene followed by a single loxP site and a thymidine kinase promoter were inserted into intron 7. Cre mediated recombination in the germ line deleted exons 2-7 and brought the thymidine kinase promoter into proximity of the EGFP gene to activate its transcription.
  • mutations:
  • Insertion,
  • Intragenic deletion
  • synonyms:
  • RA/EG<->,
  • RAGE<->.GFP,
  • Rage<->,
  • Rage<eGFP>,
  • Rage<->,
  • RAGE KO,
  • RA/EG<->,
  • RAGE-,
  • Rage<flx>,
  • Rage<eGFP>,
  • RA/EG,
  • RA/EG,
  • RAGE-,
  • RAGE<->.GFP,
  • RAGE KO,
  • Rage<flx>
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1 Feature

Trail: Allele

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

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Trail: Allele

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Trail: Allele




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