Primary Identifier | MGI:5635036 | Allele Type | Targeted |
Attribute String | Null/knockout | Gene | Cdk6 |
Transmission | Germline | Strain of Origin | Not Specified |
Is Recombinase | false | Is Wild Type | false |
description | ES cell = ESER1.56 (strain of origin not specified) |
molecularNote | Exon 1 was replaced with a modified exon 1 in which nucleotide substitution (CGC to TGC) results in the amino acid substitution of cysteine for arginine at position 31 (R31C). Mice exhibit defective expression and behave as null mice. |