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Allele : Cdk6<tm1Mama> cyclin dependent kinase 6; targeted mutation 1, Marcos Malumbres

Primary Identifier  MGI:5635036 Allele Type  Targeted
Attribute String  Null/knockout Gene  Cdk6
Transmission  Germline Strain of Origin  Not Specified
Is Recombinase  false Is Wild Type  false
description  ES cell = ESER1.56 (strain of origin not specified)
molecularNote  Exon 1 was replaced with a modified exon 1 in which nucleotide substitution (CGC to TGC) results in the amino acid substitution of cysteine for arginine at position 31 (R31C). Mice exhibit defective expression and behave as null mice.
  • mutations:
  • Insertion,
  • Single point mutation
  • synonyms:
  • Cdk6<neo>,
  • Cdk6<neo>
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1 Feature

Trail: Allele

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

0 Carried By

0 Driven By

3 Publication categories

Trail: Allele