| Primary Identifier | MGI:2657204 | Allele Type | Gene trapped |
| Attribute String | Null/knockout, Reporter | Gene | Sptbn4 |
| Transmission | Germline | Strain of Origin | 129S4/SvJaeSor |
| Is Recombinase | false | Is Wild Type | false |
| description | This mutation was identified in a gene-trap screen employing a modification of the Betageo gene trap vector, originally called Gt(ROSABgeo*), encoding aspartic acid at amino acid position 182 (Komada et al. 2000). |
| molecularNote | A gene trap vector inserted between the exons that encode the spectrin repeat 12 of the protein. Northern blot analysis demonstrated that a fusion transcript was expressed that consisted of the gene sequences and the beta-galactosidase gene of the vector. Western blot analysis on brain lysates of homozygous mice demonstrated that no detectable full length protein was made from this allele. |
