Primary Identifier | MGI:6682027 | Allele Type | Targeted |
Attribute String | Modified regulatory region | Gene | Sox2 |
Transmission | Germline | Strain of Origin | (129X1/SvJ x 129S1/Sv)F1-Kitl<+> |
Is Recombinase | false | Is Wild Type | false |
molecularNote | A loxP and neomycin resistance cassette were placed upstream of the 538 bp sequence corresponding to the N2 (neural plate 2) enhancer located 3861 bp upstream of the gene. Cre-mediated recombination removed the selection cassette and N2 enhancer. |