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Allele : Acads<Hdlq8-C57BL/6J> acyl-Coenzyme A dehydrogenase, short chain; C57BL/6J

Primary Identifier  MGI:3038140 Allele Type  QTL
Gene  Acads Inheritance Mode  Not Specified
Strain of Origin  C57BL/6J Is Recombinase  false
Is Wild Type  false
description  This allele is associted with HDL cholesterol levels on an atherogenic diet.
molecularNote  This allele confers decreased HDL cholesterol compared to NZB/BlNJ. Sequencing revealed some splice site variants and one polymorphism changing the amino acid from aspartic acid to glycine at amino acid 94. This polymorphism changes both the charge and polarity of the amino acid and is in a highly conserved region of the protein.
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1 Feature

Trail: Allele

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

0 Carried By

0 Driven By

3 Publication categories

Trail: Allele