Primary Identifier | MGI:6358014 | Allele Type | Endonuclease-mediated |
Gene | Tnfsf11 | Strain of Origin | C57BL/6 |
Is Recombinase | false | Is Wild Type | false |
molecularNote | CRISPR/Cas9 genome editing technology was used to create a deletion of sequences encoding the stalk domain, which contains all known proteolytic cleavage sites. The protein encoded by the modified allele lacks amino acids Ile133 to Ser149 and contains Arg at the former Trp150 position. |