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Allele : Dll1<em3.1(Dll4)Gos> delta like canonical Notch ligand 1; endonuclease-mediated mutation 3.1, Achim Gossler

Primary Identifier  MGI:7571318 Allele Type  Endonuclease-mediated
Attribute String  Inserted expressed sequence Gene  Dll1
Strain of Origin  129Sv and CAST/EiJ Is Recombinase  false
Is Wild Type  false
molecularNote  CRISPR-targeting introduced a DLL1 variant whose predicted amino acids of the MNNL and DSL domains that contact N1 are replaced with the corresponding amino acids of DLL4. Cre-mediated recombination removed the floxed neomycin resistance cassette.
  • mutations:
  • Insertion,
  • Intragenic deletion
  • synonyms:
  • Dll1<D1contD4ki>,
  • Dll1<D1contD4ki>
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1 Feature

Trail: Allele

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

1 Carried By

Trail: Allele

0 Driven By

2 Publication categories

Trail: Allele