Primary Identifier | MGI:3040917 | Allele Type | Targeted |
Attribute String | Null/knockout | Gene | Chrna5 |
Transmission | Germline | Strain of Origin | 129S7/SvEvBrd-Hprt1<b-m2> |
Is Recombinase | false | Is Wild Type | false |
molecularNote | Exon 5, encoding three transmembrane regions and the long intracellular loop, was replaced with a neo cassette. Northern blot confirmed absence of mRNA in mutant brains. |