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Allele : Parg<tm1Tmd> poly (ADP-ribose) glycohydrolase; targeted mutation 1, Ted M Dawson

Primary Identifier  MGI:3526553 Allele Type  Targeted
Attribute String  Null/knockout Gene  Parg
Transmission  Germline Strain of Origin  129X1/SvJ
Is Recombinase  false Is Wild Type  false
molecularNote  A cassette containing IRES-lacZ-MCneomycin replaced the 3' end of exon 4. RT-PCR analysis of total RNA from mutant embryonic trophoblast stem cells demonstrated a lack of all reported splice variants. Western blot showed the complete absence of protein.
  • mutations:
  • Intragenic deletion,
  • Insertion
  • synonyms:
  • PARG<->,
  • PARG<->
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1 Feature

Trail: Allele

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

0 Carried By

0 Driven By

5 Publication categories

Trail: Allele