| Primary Identifier | MGI:3578339 | Allele Type | Chemically induced (ENU) |
| Gene | Cryge | Inheritance Mode | Not Specified |
| Strain of Origin | (102/El x C3H/El)F1 | Is Recombinase | false |
| Is Wild Type | false |
| molecularNote | An A66G transition represses splicing of intron 1, allowing an additional 92 bp in the coding sequence that leads to a frameshift and a novel hybrid protein containing 3 amino acids of the gammaE-crystallin at the N terminus and 153 additional novel amino acids. The protein is predicted to have two hydrophobic domains and Western blot demonstrated expression in the cataractous lenses. |
