Primary Identifier | MGI:1855944 | Allele Type | Radiation induced |
Gene | a | Inheritance Mode | Other (see notes) |
Strain of Origin | (C3H/Rl x 101/Rl)F1 | Is Recombinase | false |
Is Wild Type | false |
description | ax is recessive to Ay, Aw, A, and at, and dominant to a. |
molecularNote | This allele comprises a deletion of approximately 100 kb, which does not affect agouti coding sequences, but begins 4 kb 3' of the last exon, and thus may affect coat color by removing an agouti 3' enhancer. The Ahcy gene, which codes for the enzyme S-adenosylhomocysteine hydrolase (SAHase), is contained within a 20 kb region within the a(x) deletion. |