Primary Identifier | MGI:6268775 | Allele Type | Chemically induced (ENU) |
Attribute String | Not Specified | Gene | Il4ra |
Inheritance Mode | Semidominant | Strain of Origin | C57BL/6J |
Is Recombinase | false | Is Wild Type | false |
Project Collection | Beutler Mutagenetix |
molecularNote | ENU-induced T to C transition at base pair 125,567,221 (v38) on chromosome 7, or base pair 14,940 in the GenBank genomic region NC_000073. The mutation corresponds to residue 377 in the mRNA sequence NM_001008700 within exon 4 of 11 total exons. The mutation results in a tryptophan to arginine substitution at position 46 (W46R) in the IL-4R protein. |