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Allele : Il4ra<M1Btlr> interleukin 4 receptor, alpha; mutation 1, Bruce Beutler

Primary Identifier  MGI:6268775 Allele Type  Chemically induced (ENU)
Attribute String  Not Specified Gene  Il4ra
Inheritance Mode  Semidominant Strain of Origin  C57BL/6J
Is Recombinase  false Is Wild Type  false
Project Collection  Beutler Mutagenetix
molecularNote  ENU-induced T to C transition at base pair 125,567,221 (v38) on chromosome 7, or base pair 14,940 in the GenBank genomic region NC_000073. The mutation corresponds to residue 377 in the mRNA sequence NM_001008700 within exon 4 of 11 total exons. The mutation results in a tryptophan to arginine substitution at position 46 (W46R) in the IL-4R protein.
  • mutations:
  • Single point mutation
  • synonyms:
  • Lowe,
  • Lowe
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1 Feature

Trail: Allele

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

1 Carried By

Trail: Allele

0 Driven By

3 Publication categories

Trail: Allele