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Allele : Tbs1<I/StSnEgYCit> tuberculosis severity 1; I/StSnEgYCit

Primary Identifier  MGI:2155337 Allele Type  QTL
Gene  Tbs1 Inheritance Mode  Not Specified
Strain of Origin  I/StSnEgYCit Is Recombinase  false
Is Wild Type  false
description  This locus affects M. tuberculosis-induced body weight loss in female animals.

This allele appears to interact with I/StYCit-derived alleles at D17Mit175 to increase neutrophil inflammation following challenge with M. tuberculosis.

molecularNote  The heterozygous state confers increased body weight loss and increased survival time in female animals infected with Mycobacterium tuberculosis.
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1 Feature

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

0 Carried By

0 Driven By

3 Publication categories