| Primary Identifier | MGI:6759011 | Allele Type | Targeted |
| Attribute String | Conditional ready, Humanized sequence, Inserted expressed sequence, Reporter | Gene | Ddx25 |
| Transmission | Germline | Strain of Origin | 129/SvJ |
| Is Recombinase | false | Is Wild Type | false |
| molecularNote | A cassette consisting of mouse exon 1, EGFP reporter sequence, loxP site, 2A self-cleaving peptide sequence, human DDX25 cDNA containing an arginine to histidine substitution at amino acid 242, SV40 sequence, loxP site, FRT-flanked PGK-neomycin selection cassette, and third loxP site replaced exons 1-5 of the gene. Flp-mediated recombination removed the neomycin cassette. The R242H variant is found in Japanese infertile men. |
