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Allele : Chuk<tm2Mka> conserved helix-loop-helix ubiquitous kinase; targeted mutation 2, Michael Karin
Primary Identifier  MGI:3045616 Allele Type  Targeted
Gene  Chuk Transmission  Germline
Strain of Origin  Not Specified Is Recombinase  false
Is Wild Type  false
molecularNote  Serines 176 and 180, located in exon 6, were replaced with alanines following homologous recombination. A floxed neo was excised from between exons 7 and 8 via transient Cre-mediated recombination. RT-PCR of liver tissue demonstrated expression of the mutant allele.
  • mutations:
  • Insertion
  • synonyms:
  • Ikka<AA>,
  • Ikka<AA>,
  • IKKalpha<AA>,
  • IKKalpha<AA>
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1 Feature

Trail: Allele

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

2 Carried By

Trail: Allele

0 Driven By

24 Publication categories

Trail: Allele




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