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Publication : Nox3<sup>het-5J</sup>

First Author  Bergstrom D Year  2011
Journal  Personal Communication Mgi Jnum  J:169743
Mgi Id  MGI:4941914 Citation  Bergstrom D (2011) Nox3het-5J. Personal Communication
abstractText  Failure of homozygotes to orient in a swim test was clearly observed. Homozygotes are distinctly smaller, poorly groomed, mildly kyphotic and slightly ataxic displaying a strong head tilt and jerky gait. Mutants are approximately 2/3 the size of wild type littermates. Anecdotally, some litters seem more affected than others, Nox3<het-5J> homozygotes have a wide range in their phenotype seemingly dependent on mating, litter #, and generation #. Later litters, those born to females that have already had several litters, seem to include mutants with a more severe phenotype than early litters, and mutants from homozygote x homozygote matings seem to have a more severe phenotype than those of heterozygote x heterozygote matings.
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