Primary Identifier | MGI:3768431 | Allele Type | Transgenic |
Attribute String | Inserted expressed sequence | Gene | Tg(GFAP-APOE_i4)1Vln |
Strain of Origin | FVB/N | Is Recombinase | false |
Is Wild Type | false |
molecularNote | The transgenic construct contains a GFAP promoter used to drive the expression of a cDNA encoding the human wild-type amyloid precursor protein (695 isoform). In this transgenic mouse line, human APP protein is expressed in astroglia. Another line, line gae-III (GFAP-ApoE4 line 3) was also established. |