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Heritable Phenotypic Marker : Oua1 ouabain resistance 1

Primary Identifier	MGI:97452	Organism	mouse, laboratory
Chromosome	17	Mgi Type	heritable phenotypic marker

description

PHENOTYPE: Ouabain, a glycoside with cardiac effects similar to digitalis, interacts with APTase and affects cation and amino acid transport. Cell lines carrying mouse Oua1 gene express a mutant Atp1a1 with one amino acid substitution. Oua1 shows sequence homology to upstream regulatory regions of gene Atp1a1. [provided by MGI curators]

synonyms:
MGD-MRK-13088,
ouabain resistance 1,
MGD-MRK-13089,
Oua1,
Oua-1

earliestPublication:
Coleman DL (1962) Effect of genic substitution on the incorporation of tyrosine into the melanin of mouse skin. Arch Biochem Biophys 96:562-8

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Genome

Sequence Feature Displayer

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0 Involved In Mutations

0 Transgenic Expressors

Canonical gene --> CDSs in specific strains.

Canonical gene --> Exons in specific strains

Canonical gene --> Strain-specific IDs, biotypes, and locations

Canonical gene --> Transcripts in specific strains.

Features --> Overlapping features

Proteins

Gene --> Proteins

Function

Mouse features --> Functions (GO terms)

Homology

Genes --> Homologs

Interactions

Gene --> Protein-Protein Interactions

Expression

Gene --> Expression annotations

Phenotype

Genes/Features --> Phenotypes (MP terms)

Disease

Mouse features --> Human diseases

Literature

Mouse features --> Publications

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