|  Help  |  About  |  Contact Us

Allele : Syk<tm1Paw> spleen tyrosine kinase; targeted mutation 1, Tony Pawson

Primary Identifier  MGI:1857421 Allele Type  Targeted
Attribute String  Null/knockout Gene  Syk
Transmission  Germline Strain of Origin  (129X1/SvJ x 129S1/Sv)F1-Kitl<+>
Is Recombinase  false Is Wild Type  false
molecularNote  A neomycin cassette replaced an exon that encodes 41 amino acids that are located in the subdomain VI of the kinase domain. Immunoprecipitation and western blot analysis on protein extracts derived from fetal liver showed that no SYK protein was present in homozygous mice.
  • mutations:
  • Insertion,
  • Intragenic deletion
  • synonyms:
  • Syk<->,
  • Syk<->
Quick Links:
 
Quick Links:
 

1 Feature

Trail: Allele

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

1 Carried By

Trail: Allele

0 Driven By

13 Publication categories

Trail: Allele