Primary Identifier | MGI:5499110 | Allele Type | Transgenic |
Attribute String | Humanized sequence, Inserted expressed sequence | Gene | Tg(Myl1-SOD1*G93A)#Amu |
Strain of Origin | FVB/NJ | Is Recombinase | false |
Is Wild Type | false |
molecularNote | The human SOD1 cDNA with the G93A mutation is under the control of the regulatory elements of the rat Myl1 (MLC1f/3f) gene. Western and Northern blot analysis confirmed expression in skeletal muscle, predominantly in muscles enriched in fast fibers and reduced in slow muscles such as the soleus. |