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Publication : Extracortical origin of some murine subplate cell populations.

First Author  Pedraza M Year  2014
Journal  Proc Natl Acad Sci U S A Volume  111
Issue  23 Pages  8613-8
PubMed ID  24778253 Mgi Jnum  J:211068
Mgi Id  MGI:5573091 Doi  10.1073/pnas.1323816111
Citation  Pedraza M, et al. (2014) Extracortical origin of some murine subplate cell populations. Proc Natl Acad Sci U S A 111(23):8613-8
abstractText  The subplate layer, the deepest cortical layer in mammals, has important roles in cerebral cortical development. The subplate contains heterogeneous cell populations that are morphologically diverse, with several projection targets. It is currently assumed that these cells are generated in the germinative zone of the earliest cortical neuroepithelium. Here we identify a pallial but extracortical area located in the rostromedial telencephalic wall (RMTW) that gives rise to several cell populations. Postmitotic neurons migrate tangentially from the RMTW toward the cerebral cortex. Most RMTW-derived cells are incorporated into the subplate layer throughout its rostrocaudal extension, with others contributing to the GABAergic interneuron pool of cortical layers V and VI.
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