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Allele : Cenpe<tm1Dwc> centromere protein E; targeted mutation 1, Don W Cleveland

Primary Identifier  MGI:2449007 Allele Type  Targeted
Attribute String  Null/knockout Gene  Cenpe
Transmission  Germline Strain of Origin  (129X1/SvJ x 129S1/Sv)F1-Kitl<+>
Is Recombinase  false Is Wild Type  false
molecularNote  A 120 bp exon of the gene was flanked with a loxP site and a floxed PGK-neo cassette. Transient expression of cre recombinase in correctly targeted ES cells resulted in deletion of this floxed exon and is predicted to create a premature stop codon at amino acid 82, thus producing a non-functional protein product.
  • mutations:
  • Intragenic deletion
  • synonyms:
  • CENP-E null,
  • CENP-E null
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1 Feature

Trail: Allele

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

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0 Driven By

6 Publication categories

Trail: Allele