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Allele : Elmod3<em1Jili> ELMO/CED-12 domain containing 3; endonuclease-mediated mutation 1, Jie Ling

Primary Identifier  MGI:6455516 Allele Type  Endonuclease-mediated
Attribute String  Null/knockout Gene  Elmod3
Strain of Origin  Not Specified Is Recombinase  false
Is Wild Type  false
molecularNote  CRISPR/Cas9 technology replaced exon 6 containing the start codon with a neomycin resistance gene cassette resulting in a 277 bp deletion resulting in a frameshift mutation and premature termination codon at residue 149. Western blot confirmed the absence of the protein in the cochlea.
  • mutations:
  • Insertion,
  • Intragenic deletion
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1 Feature

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

0 Carried By

0 Driven By

3 Publication categories