Primary Identifier | MGI:6455516 | Allele Type | Endonuclease-mediated |
Attribute String | Null/knockout | Gene | Elmod3 |
Strain of Origin | Not Specified | Is Recombinase | false |
Is Wild Type | false |
molecularNote | CRISPR/Cas9 technology replaced exon 6 containing the start codon with a neomycin resistance gene cassette resulting in a 277 bp deletion resulting in a frameshift mutation and premature termination codon at residue 149. Western blot confirmed the absence of the protein in the cochlea. |