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Allele : Cgas<em1Kern> cyclic GMP-AMP synthase; endonuclease-mediated mutation 1, Nagaraj Kerur
Primary Identifier  MGI:6852701 Allele Type  Endonuclease-mediated
Gene  Cgas Strain of Origin  C57BL/6J
Is Recombinase  false Is Wild Type  false
molecularNote  CRISPR/Cas9 technology generated a glycine to alanine and serine to alanine substitutions at amino acids 198 and 199 (GS198AA), generating a catalytically dead protein product.
  • mutations:
  • Nucleotide substitutions
  • synonyms:
  • cGAS<GS198AA>,
  • cGASGS198AA,
  • cGASGS198AA,
  • cGAS<GS198AA>
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1 Feature

Trail: Allele

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

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Trail: Allele

0 Driven By

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Trail: Allele




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