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Allele : Mbd2<tm1.1Joez> methyl-CpG binding domain protein 2; targeted mutation 1.1, Zhaolan Zhou
Primary Identifier  MGI:5924954 Allele Type  Targeted
Attribute String  Epitope tag Gene  Mbd2
Transmission  Germline Strain of Origin  129
Is Recombinase  false Is Wild Type  false
molecularNote  A targeting construct was designed to insert a loxP-flanked neomycin (neo) resistance cassette upstream of exon 6 of the X-linked methyl-CpG binding domain protein 2 (Mbd2) gene. A 23 amino acid Tavi tag, allowing MBD2 protein to be biotinylated in the presence of E. coli biotin ligase, BirA, was introduced immediately upstream of Mbd2 stop codon. Breeding to B6.FVB-Tg(EIIa-cre)C5379Lmgd/J transgenic mice (Stock No. 003724) removed the neo cassette.
  • mutations:
  • Insertion
  • synonyms:
  • Mbd2<Tavi>,
  • Mbd2<Tavi>
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1 Feature

Trail: Allele

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

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Trail: Allele

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Trail: Allele




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