Primary Identifier | MGI:3764659 | Allele Type | Transgenic |
Attribute String | Inserted expressed sequence | Gene | Tg(Ins2-Lta)#Flv |
Strain of Origin | (CBA x C57BL/6)F2 | Is Recombinase | false |
Is Wild Type | false |
molecularNote | A construct with the murine Lta (tumor necrosis factor-beta) gene expressed from a 600-bp fragment of the rat insulin 2 promoter (RIP) was injected into fertilized oocytes. Founders 5 (~10 copies), 16 (~100 copies), and 42 (~100 copies) were bred with C57BL/6 mice. Lta RNA was detected in pancreas, kidney and skin of transgenic mice by Northern blot. |