Primary Identifier | MGI:4443333 | Allele Type | Targeted |
Gene | Best1 | Transmission | Germline |
Strain of Origin | 129S/SvEv | Is Recombinase | false |
Is Wild Type | false |
molecularNote | Single nucleotide change was introduced to the endogenous gene by homologous recombination. The floxed neo selection cassette was introduced into intronic sequence and removed by subsequent cross with cre expressing mice. The mutation represent W93C disease causing mutation of the gene in human. |