| Primary Identifier | MGI:2667542 | Allele Type | Targeted |
| Attribute String | Null/knockout, Reporter | Gene | Ryk |
| Transmission | Germline | Strain of Origin | 129S1/Sv-Oca2<+> Tyr<+> Kitl<+> |
| Is Recombinase | false | Is Wild Type | false |
| molecularNote | A 14.5 kb genomic fragment was replaced with an IRES-betageo-pA cassette that was expected to join the endogenous exon 2 splice acceptor site. The deleted region included exons 2 through 6, which encode 95% of the extracellular domain and all of the transmembrane domain. RT-PCR and Western blot analyses indicated the absence of transcript and protein in homozygous mutant mice. |
