| Primary Identifier | MGI:4360673 | Allele Type | Transgenic |
| Attribute String | Humanized sequence, Inserted expressed sequence | Gene | Tg(Eno2-ATN1)14Tx |
| Strain of Origin | C57BL/6J x SJL/J | Is Recombinase | false |
| Is Wild Type | false |
| molecularNote | The transgene comprises a cDNA encoding full length human ATN1 containing a 118 residue polyglutamine tract, encoded by 118 CAG repeats, inserted into a transgenic vector containing the rat neuron-specific enolase promoter. This transgenic line carries two copies of the construct and, as shown by immunohistology and western blot analyses, expresses human ATN1 protein in the brain. |
