Primary Identifier | MGI:5578187 | Allele Type | Targeted |
Attribute String | Conditional ready, No functional change | Gene | Fzd6 |
Transmission | Germline | Strain of Origin | 129 |
Is Recombinase | false | Is Wild Type | false |
molecularNote | LoxP sites were inserted into introns 3 and 4 in order to flank exon 4 (the largest coding exon in the gene). A FRT-neo-FRT cassette that was used for positive selection was introduced adjacent to the loxP site in intron 3. FLP-mediated recombination removed the FRT-flanked neo cassette. |