Primary Identifier | MGI:3046260 | Allele Type | Targeted |
Attribute String | Null/knockout | Gene | Isl2 |
Transmission | Germline | Strain of Origin | 129S1/Sv-Oca2<+> Tyr<+> Kitl<+> |
Is Recombinase | false | Is Wild Type | false |
molecularNote | Exons 4, 5, and 6, which encode the homeodomain and C terminus were replaced with a neomycin resistance cassette. No protein could be detected in homozygous embryos. |