Primary Identifier | MGI:2183036 | Allele Type | Targeted |
Attribute String | Null/knockout | Gene | B3galnt1 |
Transmission | Germline | Strain of Origin | 129S6/SvEvTac |
Is Recombinase | false | Is Wild Type | false |
molecularNote | The gene was disrupted by insertion of a PGK-neo cassette 140 bp downstream of the ATG start codon via homologous recombination, resulting in the deletion of the entire C-terminal region after amino acid 47 in the encoded protein. Genotype analysis detected homozygous mutant embryos at 3.5 days post coitum. No homozygous mutant animals could be recovered. |