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Allele : Vav2<tm1.1Geno> vav 2 oncogene; targeted mutation 1.1, Genoway

Primary Identifier  MGI:6758212 Allele Type  Targeted
Attribute String  Conditional ready, No functional change Gene  Vav2
Transmission  Germline Strain of Origin  Not Specified
Is Recombinase  false Is Wild Type  false
molecularNote  The targeting mutation inserted a lox511 site upstream of the endogenous exon 11 and an FRT-flanked neomycin resistance cassette inserted downstream of exon 11 followed by a floxed and inverted exon 11 with the amino acid substitution of leucine with alanine at position 332 (L332A) and a lox511 site. Flp-mediated recombination removed the FRT-flanked neomycin resistance cassette.
  • mutations:
  • Nucleotide substitutions,
  • Insertion
  • synonyms:
  • Vav2<f>,
  • Vav2<f>
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1 Feature

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

0 Carried By

0 Driven By

3 Publication categories